The houses of Panama arc so constructed and of such material and so filthy that a general conflagration would be the onlysafe means of disinfection. I can not cnceive of any other means by which the infection could be eradicated. There are four regular lines of steamships that enter and sail from Panama each week and tramps and siling vessels drop in occasionally. The teritory tributary to Panama is from Valparaiso. Chile. to San Francisco. Cal.. Asiatic goods being transshipped in an b Francisco. There are no quarantine restrictions in Panama. not even an inspector. I entered the port twice. once from Central America and once from Guayaquil.